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PXD011680-3

PXD011680 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleIntermolecular Architecture of Fibrin Clots and its Interaction INterface with Albumin
DescriptionIn this project we establish the unit cell of fibrin polymer network by using of XL-MS methods and modelling approaches. With shotgun proteomics approach we estimate the ratio of proteins in the purified Fibrin Clots and ratio of Albumin inter- and intralinks
HostingRepositoryPRIDE
AnnounceDate2020-01-09
AnnouncementXMLSubmission_2020-02-17_02:25:49.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterOleg Klykov
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListmonohydroxylated residue; iodoacetamide derivatized residue
InstrumentOrbitrap Fusion Lumos; Q Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02018-11-13 05:36:02ID requested
12020-01-09 10:15:41announced
22020-01-17 06:12:20announced2020-01-17: Updated publication reference for PubMed record(s): 31924745.
32020-02-17 02:25:51announced2020-01-17: Updated publication reference for PubMed record(s): 31924745.
2020-02-17: Updated publication reference for PubMed record(s): 31924745.
42020-11-06 08:13:19announced2020-11-06: Updated project metadata.
52022-02-13 16:19:16announced2022-02-14: Updated project metadata.
62022-02-13 16:27:29announced2022-02-14: Updated project metadata.
72024-10-22 04:55:08announced2024-10-22: Updated project metadata.
Publication List
Klykov O, van der Zwaan C, Heck AJR, Meijer AB, Scheltema RA, Missing regions within the molecular architecture of human fibrin clots structurally resolved by XL-MS and integrative structural modeling. Proc Natl Acad Sci U S A, 117(4):1976-1987(2020) [pubmed]
Keyword List
submitter keyword: XL-MS, DSSO, Modeling, Docking, Fibrin, Fibrinogen, Albumin
Contact List
Albert J. R. Heck
contact affiliationDistinguished Faculty Professor Utrecht University Scientific Director Netherlands Proteomics Centre and Scientific Director Utrecht Institute for Pharmaceutical Sciences Biomolecular Mass Spectrometry and Proteomics Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences Utrecht University Padualaan 8, 3584 CH Utrecht, The Netherlands
contact emailA.J.R.Heck@uu.nl
lab head
Oleg Klykov
contact affiliationUtrecht University
contact emailo.klykov@uu.nl
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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