PXD011593-1

PXD011593 is an original dataset announced via ProteomeXchange.

Title	Protein-based Cardiogenic Shock Patient Classifier
Description	Cardiogenic shock (CS) is associated with high short-term mortality and a precise CS risk stratification could guide interventions to improve patient outcome. A 4-protein risk score (CS4P) was derived and validated for 90-day risk of mortality. The CS4P risk score, which comprises proteins Liver-fatty acid-binding protein (L-FABP), Beta-2-microglobulin (B2MG), Fructose-bisphosphate aldolase B (ALDOB), and SerpinG1 (IC1), identified short-term mortality risk with a C-statistic of 0.83 (95% CI 0.74–0.89). CS4P patient classifier performed better than contemporary risk scores. In CS a prompt risk stratification using the CS4P patient classifier guide clinicians in selecting patients for advanced therapies
HostingRepository	PanoramaPublic
AnnounceDate	2021-01-24
AnnouncementXML	Submission_2021-01-24_15:44:50.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	supported by repository but incomplete data and/or metadata
PrimarySubmitter	Cristina Chiva
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	Carbamidomethyl; Label:13C(6)15N(2); Label:13C(6)15N(4)
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2018-11-06 10:58:26	ID requested
⏵ 1	2021-01-24 15:44:50	announced

Rueda F, Borr, à, s E, Garc, í, a-Garc, í, a C, Iborra-Egea O, Revuelta-L, ó, pez E, Harjola VP, Cediel G, Lassus J, Tarvasm, ä, ki T, Mebazaa A, Sabid, ó E, Bay, é, s-Gen, í, s A, Protein-based cardiogenic shock patient classifier. Eur Heart J, 40(32):2684-2694(2019) [pubmed]

submitter keyword: Cardiogenic Shock, PRM

Eduard Sabidó
contact affiliation	Center for Genomic Regulation (CRG)
contact email	eduard.sabido@crg.cat
lab head
Cristina Chiva
contact affiliation	University Pompeu Fabra
contact email	cristina.chiva@upf.edu
dataset submitter

Panorama Public dataset URI