PXD011010 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Identification of proteins associated with Kv1.2 potassium channels. |
Description | Kv1.2 is a prominent voltage-gated potassium channel that influences action potential generation and propagation in the central nervous system. We explored multi-protein complexes containing Kv1.2 using mass spectrometry of immunoprecipitated samples. Proteins identified as candidate interactors were prioritized based on abundance, and were screened for functional effects on Kv1.2 channels using electrophysiology. |
HostingRepository | PRIDE |
AnnounceDate | 2018-11-04 |
AnnouncementXML | Submission_2018-11-04_15:51:33.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Jenny Moon |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | Bruker Daltonics instrument model |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2018-09-05 05:43:17 | ID requested | |
⏵ 1 | 2018-11-04 15:51:34 | announced | |
Publication List
Baronas VA, Yang RY, Morales LC, Sipione S, Kurata HT, Slc7a5 regulates Kv1.2 channels and modifies functional outcomes of epilepsy-linked channel mutations. Nat Commun, 9(1):4417(2018) [pubmed] |
Keyword List
curator keyword: Biological |
submitter keyword: human, Kv1.2, potassium channel, LCMSMS |
Contact List
Harley Takatsuna Kurata |
contact affiliation | Department of Pharmacology, Alberta Diabetes Institute, University of Alberta |
contact email | kurata@ualberta.ca |
lab head | |
Jenny Moon |
contact affiliation | University of British Columbia |
contact email | kyungmee@mail.ubc.ca |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/11/PXD011010 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD011010
- Label: PRIDE project
- Name: Identification of proteins associated with Kv1.2 potassium channels.