PXD010972 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | rat cecal microbiota LC-MSMS . |
Description | Pu-erh tea has attracted increasing attention worldwide because of its special flavor and health effects, but its impact on composition and function of the gut microbiota remains unclear. The aim of this study was to investigate effects of aqueous extracts of fermented (ripe) and non-fermented (raw) Pu-erh teas on the composition and function of intestinal microbiota of rats with diet-induced obesity. We conducted a comparative metagenomic and metaproteomic investigation of the microbial communities in cecal samples taken from obese rats administrated with or without extracts of raw and ripe Pu-erh tea. By analyzing the composition and diversity of 16S rRNA amplicons and expression profiles of 814 distinct proteins, we found that, despite differences in the chemical compositions of the raw and ripe Pu-erh tea, administration of either at two different doses (0.15 and 0.40 g/Kg body weight), significantly (P<0.05) increased community diversity, and changed the composition of the cecal microbiota by increasing the relative abundances of Firmicutes and decreasing those of Bacteroidetes. Community metabolic processes including sucrose metabolism, glycolysis, syntheses of proteins, rRNA and antibiotics were significantly (P<0.05), or had a tendency (0.10 |
HostingRepository | PRIDE |
AnnounceDate | 2024-10-07 |
AnnouncementXML | Submission_2024-10-07_10:18:08.894.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Yunhong Kong |
SpeciesList | scientific name: Microbiota; NCBI TaxID: 13613; |
ModificationList | No PTMs are included in the dataset |
Instrument | Q Exactive HF-X |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2018-08-31 05:38:51 | ID requested | |
⏵ 1 | 2024-10-07 10:18:09 | announced | |
Publication List
Keyword List
ProteomeXchange project tag: Glycoproteomics (B/D-HPP) |
curator keyword: Biological |
submitter keyword: LC-MSMS, cecal microbiota, Pu-erh tea,Wista rats |
Contact List
Yunhong Kong |
contact affiliation | Department of Biology and Technology, Kunming University, Kunming, China |
contact email | kongyunhong22@163.com |
lab head | |
Yunhong Kong |
contact affiliation | Department of Biology and Technology |
contact email | kongyunhong22@163.com |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD010972
- Label: PRIDE project
- Name: rat cecal microbiota LC-MSMS