PXD010972-1

PXD010972 is an original dataset announced via ProteomeXchange.

Title	rat cecal microbiota LC-MSMS .
Description	Pu-erh tea has attracted increasing attention worldwide because of its special flavor and health effects, but its impact on composition and function of the gut microbiota remains unclear. The aim of this study was to investigate effects of aqueous extracts of fermented (ripe) and non-fermented (raw) Pu-erh teas on the composition and function of intestinal microbiota of rats with diet-induced obesity. We conducted a comparative metagenomic and metaproteomic investigation of the microbial communities in cecal samples taken from obese rats administrated with or without extracts of raw and ripe Pu-erh tea. By analyzing the composition and diversity of 16S rRNA amplicons and expression profiles of 814 distinct proteins, we found that, despite differences in the chemical compositions of the raw and ripe Pu-erh tea, administration of either at two different doses (0.15 and 0.40 g/Kg body weight), significantly (P<0.05) increased community diversity, and changed the composition of the cecal microbiota by increasing the relative abundances of Firmicutes and decreasing those of Bacteroidetes. Community metabolic processes including sucrose metabolism, glycolysis, syntheses of proteins, rRNA and antibiotics were significantly (P<0.05), or had a tendency (0.10
HostingRepository	PRIDE
AnnounceDate	2024-10-07
AnnouncementXML	Submission_2024-10-07_10:18:08.894.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Yunhong Kong
SpeciesList	scientific name: Microbiota; NCBI TaxID: 13613;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF-X

Revision	Datetime	Status	ChangeLog Entry
0	2018-08-31 05:38:51	ID requested
⏵ 1	2024-10-07 10:18:09	announced

10.1007/S00253-018-09581-2;

ProteomeXchange project tag: Glycoproteomics (B/D-HPP)

curator keyword: Biological

submitter keyword: LC-MSMS, cecal microbiota, Pu-erh tea,Wista rats

Yunhong Kong
contact affiliation	Department of Biology and Technology, Kunming University, Kunming, China
contact email	kongyunhong22@163.com
lab head
Yunhong Kong
contact affiliation	Department of Biology and Technology
contact email	kongyunhong22@163.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/03/PXD010972

PRIDE project URI

• PRIDE
  1. PXD010972
     1. Label: PRIDE project
     2. Name: rat cecal microbiota LC-MSMS