PXD010950 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | 4 RABs proxymity labelling |
Description | APEX2-mediated proximity labeling was performed with 4 endosomal RABs allowed an efficient and comprehensive identification of their protein neighbors. APEX2-mediated proximity labeling was performed in triplicate. Protein enrichments obtained from all RABs were compared to APEX2-nude proximity labeling results. Finally, bioinformatic and biochemical approaches were used to confirm functional validity of RAB protein neighbor’s identification. |
HostingRepository | PRIDE |
AnnounceDate | 2019-01-07 |
AnnouncementXML | Submission_2019-01-07_05:40:00.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Tomas Del Olmo |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | monohydroxylated residue; acetylated residue; iodoacetamide derivatized residue |
Instrument | LTQ Orbitrap |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2018-08-30 08:24:10 | ID requested | |
⏵ 1 | 2019-01-07 05:40:02 | announced | |
Publication List
Del Olmo T, Lauzier A, Normandin C, Larcher R, Lecours M, Jean D, Lessard L, Steinberg F, Boisvert FM, Jean S, APEX2-mediated RAB proximity labeling identifies a role for RAB21 in clathrin-independent cargo sorting. EMBO Rep, 20(2):(2019) [pubmed] |
Keyword List
curator keyword: Biological |
submitter keyword: RABs, APEX2, Membrane trafficking, Early endosomes |
Contact List
steve jean |
contact affiliation | université de sherbrooke |
contact email | steve.jean@usherbrooke.ca |
lab head | |
Tomas Del Olmo |
contact affiliation | université de Sherbrooke |
contact email | tomas.del.olmo@usherbrooke.ca |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/01/PXD010950 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD010950
- Label: PRIDE project
- Name: 4 RABs proxymity labelling