PXD010916-1
PXD010916 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | SAINT_3727_JQ1_APMS_endoK562_P82_VS17_28AUG2018 |
Description | This submission contains the mass spectrometry files for the manuscript by Lambert, Picaud et al. that describes the characterization of interactome changes induced by JQ1 on the BET proteins. This submission contains 16 files associated with endogenous IP-MS analysis of BRD2, BRD3 and BRD4 (IgG was used as a negative control) from K562 cells treated with (+)-JQ1 or DMSO for 1 h; biological duplicate analyses were performed. Sample were analysed on a TripleTOF 5600 spectrometer; please note that the SWATH/DIA files were used for quantification (MSPLIT-DIA) while the DDA files were used for library construction. See the README file within "Materials and Methods" and the accompanying files for a complete description of MS data generated. |
HostingRepository | MassIVE |
AnnounceDate | 2018-10-15 |
AnnouncementXML | Submission_2018-10-15_17:32:52.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Supported dataset by repository |
PrimarySubmitter | Gingras Lab |
SpeciesList | scientific name: Homo sapiens; common name: human; NCBI TaxID: 9606; |
ModificationList | Oxidation; deaminated residue |
Instrument | TripleTOF 5600 |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2018-08-28 14:03:15 | ID requested | |
⏵ 1 | 2018-10-15 17:32:52 | announced |
Publication List
Jean-Philippe Lambert, Sarah Picaud, Takao Fujisawa, Huayun Hou, Pavel Savitsky, Liis Uusküla-Reimand, Gagan D. Gupta, Hala Abdouni, Zhen-Yuan Lin, Monika Tucholska, James D.R. Knight, Beatriz Gonzalez-Badillo, Nicole St-Denis, Joseph A. Newman, Manuel Stucki, Laurence Pelletier, Nuno Bandeira, Michael D. Wilson, Panagis Filippakopoulos, Anne-Claude Gingras. Interactome rewiring following pharmacological targeting of BET bromodomains. Mol Cell, in press. |
Keyword List
submitter keyword: BET proteins, endogenous IP-MS |
Contact List
Anne-Claude Gingras | |
---|---|
contact affiliation | LTRI |
contact email | gingras@lunenfeld.ca |
lab head | |
Gingras Lab | |
contact affiliation | Samuel Lunenfeld Research Institute |
contact email | gingras@mshri.on.ca |
dataset submitter |
Full Dataset Link List
MassIVE dataset URI |
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/MSV000082859 |