PXD010901-1

PXD010901 is an original dataset announced via ProteomeXchange.

Title	Further evidence for sustainable alternatives to replace threatened animal horn based on quantitative proteomic analysis
Description	In the present study, a quantitative proteomic approach was used to analyse and compare the proteome in horns from endangered species (rhinoceros, Saiga antelope, and Tibetan antelope) and common species (yak, water buffalo, and goat) based on the isobaric tag for relative and absolute quantification (iTRAQ) techniques. In total, 591 proteins were identified, and 321 were quantified and categorised based on molecular function, cellular component, and biological process. Principal component analysis (PCA) and hierarchical clustering analysis (HCA) results based on differences in the amount of protein identified three major clusters, and proteins including transglutaminase, desmocollin, and elongation factors were selected as trait components from proteomic patterns of horn samples from different species. Quantitative proteomic analysis-based strategies can therefore provide further evidence for sustainable alternatives to replace animal horn from threatened species.
HostingRepository	PRIDE
AnnounceDate	2022-03-02
AnnouncementXML	Submission_2022-03-02_02:50:36.338.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Rui Liu
SpeciesList	scientific name: Laurasiatheria; NCBI TaxID: 314145;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2018-08-28 07:10:48	ID requested
⏵ 1	2022-03-02 02:50:36	announced
2	2024-10-22 05:34:54	announced	2024-10-22: Updated project metadata.

Dataset with its publication pending

curator keyword: Biological

submitter keyword: iTRAQ, proteomics, animal horn, principal component analysis, clustering

Rui Liu
contact affiliation	Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, and National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine, Nanjing 210023, PR China
contact email	cpulr@126.com
lab head
Rui Liu
contact affiliation	Nanjing University of Chinese Medicine
contact email	cpulr@126.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/03/PXD010901

PRIDE project URI

• PRIDE
  1. PXD010901
     1. Label: PRIDE project
     2. Name: Further evidence for sustainable alternatives to replace threatened animal horn based on quantitative proteomic analysis