PXD010717-1

PXD010717 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	A cross-linking-aided mass spectrometry workflow reveals extensive intracellular trafficking in time-resolved, signal-dependent EGFR proteome
Description	Here we describe a cross-linking-aided MS workflow for isolation and identification of signal-dependent membrane protein interactomes using EGFR as an example. Employing formaldehyde as a cross-linking reagent, we performed immuno-precipitation of endogenous EGFR upon EGF treatment, facilitating the capture of weak and transient interactions in the proximity of the receptor, and analyzed the associated proteins by quantitative mass spectrometry.
HostingRepository	MassIVE
AnnounceDate	2018-10-30
AnnouncementXML	Submission_2018-10-30_15:35:16.xml
DigitalObjectIdentifier
ReviewLevel	Non peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Sung Yun Jung
SpeciesList	scientific name: Homo sapiens; common name: human; NCBI TaxID: 9606;
ModificationList	Oxidation
Instrument	Orbitrap Fusion

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2018-08-07 23:52:38	ID requested
⏵ 1	2018-10-30 15:35:17	announced

Publication List

no publication

no publication

Keyword List

submitter keyword: EGFR

submitter keyword: EGFR

Contact List

Yi Wang
contact affiliation	Baylor College of Medicine
contact email	yiw@bcm.edu
lab head
Sung Yun Jung
contact affiliation	Baylor College of Medicine
contact email	syjung@bcm.edu
dataset submitter

Full Dataset Link List

MassIVE dataset URI
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MassIVE dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/MSV000082799