PXD010691 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | PLASMA PROTEOMIC ANALYSIS OF RARE BMI-DISCORDANT MONOZYGOTIC TWIN PAIRS |
Description | The aim of the current study is to establish the effect of excess body wiehgt and liver fat on plasma proteomic profile without interference from genetic variation. Label-free proteomics (HDMSE) was performed on plasma samples of young healthy monozygotic twins who were discordant for BMI. the twins were further subdivided into groups of liver fat discordant and liver fat concordant to see the efefct fo liver fat on plasma proteomic signature. |
HostingRepository | PRIDE |
AnnounceDate | 2024-10-22 |
AnnouncementXML | Submission_2024-10-22_04:47:17.979.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Sakari Joenväärä |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | monohydroxylated residue; iodoacetamide derivatized residue |
Instrument | Synapt MS |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2018-08-06 04:00:24 | ID requested | |
1 | 2019-02-01 16:54:04 | announced | |
⏵ 2 | 2024-10-22 04:47:20 | announced | 2024-10-22: Updated project metadata. |
Publication List
10.1002/prca.201800173; |
Sahebekhtiari N, Saraswat M, Joenv, ä, ä, r, ä S, Jokinen R, Lovric A, Kaye S, Mardinoglu A, Rissanen A, Kaprio J, Renkonen R, Pietil, ä, inen KH, Plasma Proteomics Analysis Reveals Dysregulation of Complement Proteins and Inflammation in Acquired Obesity-A Study on Rare BMI-Discordant Monozygotic Twin Pairs. Proteomics Clin Appl, 13(4):e1800173(2019) [pubmed] |
Keyword List
ProteomeXchange project tag: Liver (B/D-HPP) |
curator keyword: Biological |
submitter keyword: HDMSE, Plasma proteomics,Monozygotic twins, Label-free proteomics, Acquired Obesity, Complement activation |
Contact List
Risto Renkonen |
contact affiliation | Transplantation laboratory, Faculty of Medicine, University of Helsinki, Helsinki, 00290, Finland |
contact email | risto.renkonen@helsinki.fi |
lab head | |
Sakari Joenväärä |
contact affiliation | Helsinki University |
contact email | sakari.joenvaara@helsinki.fi |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD010691
- Label: PRIDE project
- Name: PLASMA PROTEOMIC ANALYSIS OF RARE BMI-DISCORDANT MONOZYGOTIC TWIN PAIRS