PXD010669-1

PXD010669 is an original dataset announced via ProteomeXchange.

Title	Necator americanus secretome - In the current project we have carried out the first proteogenomic analysis of a parasitic helminth
Description	In the current project we have carried out the first proteogenomic analysis of a parasitic helminth. This has allowed us to significantly improve the genome annotation and provide a robust characterisation of the ES proteome from the adult N. americanus. Our findings show important information on key families of proteins with both known and unknown functions which may be instrumental for host-parasite interactions, parasite survival and immune regulation. Description of these proteins is useful for informing future identification of vaccine and drug targets, diagnostics and novel therapeutics for treating autoimmune and allergic diseases.
HostingRepository	PRIDE
AnnounceDate	2020-04-02
AnnouncementXML	Submission_2020-06-01_16:50:42.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD010669
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Javier Sotillo
SpeciesList	scientific name: Necator americanus; NCBI TaxID: 51031;
ModificationList	No PTMs are included in the dataset
Instrument	TripleTOF 5600

Revision	Datetime	Status	ChangeLog Entry
0	2018-08-03 01:39:21	ID requested
⏵ 1	2020-06-01 16:50:43	announced

Logan J, Pearson MS, Manda SS, Choi YJ, Field M, Eichenberger RM, Mulvenna J, Nagaraj SH, Fujiwara RT, Gazzinelli-Guimaraes P, Bueno L, Mati V, Bethony JM, Mitreva M, Sotillo J, Loukas A, hookworms. PLoS Negl Trop Dis, 14(5):e0008237(2020) [pubmed]

curator keyword: Biological, Biomedical

submitter keyword: Necator americanus, secretome, proteins, proteogenomics, secretory products

Alex Loukas
contact affiliation	Australian Institute of Tropical Health and Medicine James Cook University
contact email	alex.loukas@jcu.edu.au
lab head
Javier Sotillo
contact affiliation	James Cook University
contact email	javier.sotillo@jcu.edu.au
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/09/PXD010669

PRIDE project URI

• PRIDE
  1. PXD010669
     1. Label: PRIDE project
     2. Name: Necator americanus secretome - In the current project we have carried out the first proteogenomic analysis of a parasitic helminth