PXD010608 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Plasma Proteome Dynamics in the Pig Model of Trauma |
Description | The effect of IV-adminstered Vitamin C on the plasma proteome in the pig trauma model was investigated with label free proteomics. Plasma samples were drawn from 9 male Sinclair swine at baseline, post-trauma, and 0.25, 2, and 4 hourspost resuscitation with 500 mL of hydroxyethyl starch. Swine were randomized to receive either saline, low-dose VitC (50 mg/kg), or high-dose VitC (200 mg/kg) during volume resuscitation (N = 3/treatment). High performance LC-MS/MS proteomics was then used to quantitatively measure plasma protein fluctations over time as a function of treatment. |
HostingRepository | PRIDE |
AnnounceDate | 2022-03-11 |
AnnouncementXML | Submission_2022-03-10_17:52:05.253.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Adam Hawkridge |
SpeciesList | scientific name: Sus scrofa domesticus (domestic pig); NCBI TaxID: 9825; |
ModificationList | monohydroxylated residue; iodoacetamide derivatized residue; deamidated residue |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2018-07-30 02:09:54 | ID requested | |
⏵ 1 | 2022-03-10 17:52:05 | announced | |
2 | 2023-11-14 08:49:41 | announced | 2023-11-14: Updated project metadata. |
Publication List
Keyword List
curator keyword: Biomedical |
submitter keyword: Trauma, Vitamin C, Proteomics, ADAMTS13, VWF, Plasma |
Contact List
Adam Hawkridge |
contact affiliation | Department of Pharmaceutics and Pharmacotherapy |
contact email | amhawkridge@vcu.edu |
lab head | |
Adam Hawkridge |
contact affiliation | Virginia Commonwealth University |
contact email | amhawkridge@vcu.edu |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/03/PXD010608 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD010608
- Label: PRIDE project
- Name: Plasma Proteome Dynamics in the Pig Model of Trauma