PXD009841-1
PXD009841 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | The MS data for Walker-256 lung metastasis rat model by Orbitrap Fusion Lumos |
| Description | We performed a lung metastasis of a rat model was established by tail-vein injection of Walker-256 cells. Urine samples were collected at days 2, 4, 6 and 9 after injection, and the urinary proteomes were profiled. On days 2, 4, 6 and 9, 11, 25, 34 and 44 differential proteins were identified in 7 lung metastatic rats. Seventeen and 18 differential proteins were identified on the second day and the fourth day respectively, and all these 17 and 18 differential proteins had been reported to associate with both lung cancer and breast cancer. A total of 9 differential proteins were identified in all 7 lung metastatic rats at more than one time point but none of them were identified in the subcutaneous rat model. Our results indicate that (1) the urine proteome changed significantly, even on the second day after tail-vein injection of Walker-256 cells and that (2) the urinary differential proteins were different in Walker-256 lung metastatic and subcutaneous models. |
| HostingRepository | iProX |
| AnnounceDate | 2018-05-19 |
| AnnouncementXML | Submission_2018-05-20_19:09:59.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Jing Wei |
| SpeciesList | scientific name: Rattus norvegicus; NCBI TaxID: 10116; |
| ModificationList | iodoacetamide derivatized residue; monohydroxylated residue |
| Instrument | Orbitrap Fusion |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2018-05-20 19:09:45 | ID requested | |
| ⏵ 1 | 2018-05-20 19:10:00 | announced |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: Cancer Metastasis, Biomarkers Urine Proteome |
Contact List
| Youhe Gao | |
|---|---|
| contact affiliation | Department of Biochemistry and Molecular Biology, Beijing Normal University, Gene Engineering Drug and Biotechnology Beijing Key Laboratory |
| contact email | gaoyouhe@bnu.edu.cn |
| lab head | |
| Jing Wei | |
| contact affiliation | Department of Biochemistry and Molecular Biology, Beijing Normal University, Gene Engineering Drug and Biotechnology Beijing Key Laboratory, Beijing, 100875, China |
| contact email | weijingbnu@mail.bnu.edu.cn |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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