PXD009654-1

PXD009654 is an original dataset announced via ProteomeXchange.

Title	Human serum glycosylation
Description	In this work, we presented an integrated workflow for simultaneous analysis of sialylated glycosites and site-specific glycoforms by taking advantages of SGP enrichment approach with high specificity and paired spectra intact glycopeptide identification strategy with high efficiency. By using this strategy, comprehensive analysis of sialylation of glycoproteins was achieved, which could reveal the high heterogeneity of sialylated glycosylation. Additionally, significant changes were obtained on the levels of sialylated glycosites, as well as site-specific glycoforms between pooled hepatocellular carcinoma (HCC) and normal human serum samples. Taken together, our method could be a powerful tool for comprehensive analysis of sialylation glycosylation in human serum and other biological samples.
HostingRepository	iProX
AnnounceDate	2018-05-03
AnnouncementXML	Submission_2018-05-02_23:23:13.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Hongqiang Qin
SpeciesList	scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList	deaminated residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2018-05-02 23:22:54	ID requested
⏵ 1	2018-05-02 23:23:13	announced

Dataset with its publication pending

submitter keyword: Human serum, site-specific glycosylation, sialylation

Mingliang Ye
contact affiliation	Dalian Institute of Chemical Physics, CAS
contact email	mingliang@dicp.ac.cn
lab head
Hongqiang Qin
contact affiliation	Dalian Institute of Chemical Physics, CAS
contact email	qinhongqiang2004@126.com
dataset submitter

iProX dataset URI