PXD009531 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Unveiling the Peptide Motifs of HLA-C and HLA-G from Naturally Presented Peptides and Generation of Binding Prediction Matrices |
Description | The classical HLA-C and the nonclassical HLA-E and HLA-G molecules play important roles both in the innate and adaptive immune system. Starting already during embryogenesis and continuing throughout our lives, these three Ags exert major functions in immune tolerance, defense against infections, and anticancer immune responses. Despite these important roles, identification and characterization of the peptides presented by these molecules has been lacking behind the more abundant HLA-A and HLA-B gene products. In this study, we elucidated the peptide specificities of these HLA molecules using a comprehensive analysis of naturally presented peptides. |
HostingRepository | PRIDE |
AnnounceDate | 2018-04-20 |
AnnouncementXML | Submission_2018-04-20_05:42:25.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Michael Ghosh |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | Orbitrap Fusion Lumos |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2018-04-18 07:21:51 | ID requested | |
⏵ 1 | 2018-04-20 05:42:26 | announced | |
Publication List
Di Marco M, Schuster H, Backert L, Ghosh M, Rammensee HG, Stevanovi, ć S, Unveiling the Peptide Motifs of HLA-C and HLA-G from Naturally Presented Peptides and Generation of Binding Prediction Matrices. J Immunol, 199(8):2639-2651(2017) [pubmed] |
Keyword List
curator keyword: Biological, Biomedical |
submitter keyword: LC-MSMS, HLA-C, HLA-G, HLA-E, Binding Prediction |
Peptide Motifs |
Contact List
Stefan Stevanovic |
contact affiliation | Department of Immunology, Interfaculty Institute for Cell Biology, Tübingen, Germany |
contact email | stefan.stevanovic@uni-tuebingen.de |
lab head | |
Michael Ghosh |
contact affiliation | Department of Immunology, Tübingen |
contact email | Michaelghosh@gmx.de |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/04/PXD009531 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD009531
- Label: PRIDE project
- Name: Unveiling the Peptide Motifs of HLA-C and HLA-G from Naturally Presented Peptides and Generation of Binding Prediction Matrices