PXD009495-2

PXD009495 is an original dataset announced via ProteomeXchange.

Title	Thermal proteome profiling in Escherichia coli
Description	We adapted thermal proteome profiling (TPP) to study the thermostability of Escherichia coli proteins in vivo. We monitored the E. coli meltome and proteome at different growth phases, in a tolC knock-out mutant and after drug treatment.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_04:44:24.209.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Andre Mateus
SpeciesList	scientific name: Escherichia coli; NCBI TaxID: 562; scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	TMT6plex-126 reporter+balance reagent acylated residue; acetylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2018-04-13 02:20:39	ID requested
1	2018-07-09 00:22:35	announced
⏵ 2	2024-10-22 04:44:32	announced	2024-10-22: Updated project metadata.

10.15252/msb.20188242;

Mateus A, Bobonis J, Kurzawa N, Stein F, Helm D, Hevler J, Typas A, Savitski MM, . Mol Syst Biol, 14(7):e8242(2018) [pubmed]

ProteomeXchange project tag: benchmarking, machine learning

curator keyword: Biological

submitter keyword: target engagement, Escherichia coli, drugs, growth phase, meltome,thermal proteome profiling

Mikhail M. Savitski
contact affiliation	European Molecular Biology Laboratory
contact email	mikhail.savitski@embl.de
lab head
Andre Mateus
contact affiliation	European Molecular Biology Laboratory
contact email	andre.mateus@embl.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/07/PXD009495

PRIDE project URI

• PRIDE
  1. PXD009495
     1. Label: PRIDE project
     2. Name: Thermal proteome profiling in Escherichia coli