PXD009399 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | TMT-based quantitative proteomics of plasma from chicken challenged with lipopolysaccharide endotoxin |
Description | The change in the plasma proteome in chicken (Gallus gallus) challenged with lipopolysaccharide (endotoxin) derived from E. coli was determined by relative quantitation using a TMT label-based approach. This study provides insights into different factors contributing to innate immune response to experimental infection during 72 hours with special emphasis on acute phase proteins (APPs). Apart from APPs, several pathways endopeptidase activation and vasoconstriction were found to be significant. |
HostingRepository | PRIDE |
AnnounceDate | 2024-10-22 |
AnnouncementXML | Submission_2024-10-22_04:44:10.870.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Anita Horvatic |
SpeciesList | scientific name: Gallus gallus (Chicken); NCBI TaxID: 9031; |
ModificationList | TMT6plex-126 reporter+balance reagent acylated residue; iodoacetamide derivatized residue |
Instrument | Q Exactive Plus |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2018-04-04 08:31:17 | ID requested | |
1 | 2018-08-20 02:55:21 | announced | |
⏵ 2 | 2024-10-22 04:44:13 | announced | 2024-10-22: Updated project metadata. |
Publication List
10.1016/j.jprot.2018.08.009; |
Horvati, ć A, Guillemin N, Kaab H, McKeegan D, O'Reilly E, Bain M, Kule, š J, Eckersall PD, Quantitative proteomics using tandem mass tags in relation to the acute phase protein response in chicken challenged with Escherichia coli lipopolysaccharide endotoxin. J Proteomics, 192():64-77(2019) [pubmed] |
Keyword List
curator keyword: Biological |
submitter keyword: TMT, lipopolysaccharide endotoxin infection, plasma,Chicken, quantitative proteomics |
Contact List
David Eckersall |
contact affiliation | ERA Chair laboratory, Internal Diseases Clinic, Faculty of Veterinary Medicine, University of Zagreb, Croatia |
contact email | David.Eckersall@glasgow.ac.uk |
lab head | |
Anita Horvatic |
contact affiliation | University of Zagreb, Faculty of Veterinary Medicine |
contact email | horvatic.ani@gmail.com |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD009399
- Label: PRIDE project
- Name: TMT-based quantitative proteomics of plasma from chicken challenged with lipopolysaccharide endotoxin