PXD009394-1

PXD009394 is an original dataset announced via ProteomeXchange.

Title	Characterization of a nonhuman primate model for the study of testicular peritubular cells – comparison with human testicular cells
Description	Smooth-muscle-like peritubular cells make up the wall of semniferous tubules of men. These human testicular peritubular cells (HTPC) have been shown to fulfill different roles. They transport sperm, secrete various factors like GDNF (glial cell line derived neurotrophic factor) and are immunologically active. They might contribute to spermatogonial stem cell niche altering and testicular ageing. Previous studies were limited regarding heterogeneity (due to lifestyle, age, medical history etc.) and accessibility of HTPCs. To circumvent this problem a cellular primate model should be established. The proteome of 6 MKTPCs of individual healthy and young (2 or 3 years) donors was assessed to investigate the suitability as a model.
HostingRepository	PRIDE
AnnounceDate	2018-06-06
AnnouncementXML	Submission_2018-06-06_06:29:00.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Jan Bernd Stöckl
SpeciesList	scientific name: Callithrix jacchus; NCBI TaxID: 9483;
ModificationList	iodoacetamide derivatized residue
Instrument	TripleTOF 5600

Revision	Datetime	Status	ChangeLog Entry
0	2018-04-04 04:12:03	ID requested
⏵ 1	2018-06-06 06:29:01	announced

Schmid N, St, ö, ckl JB, Flenkenthaler F, Dietrich KG, Schwarzer JU, K, ö, hn FM, Drummer C, Fr, ö, hlich T, Arnold GJ, Behr R, Mayerhofer A, Characterization of a non-human primate model for the study of testicular peritubular cells-comparison with human testicular peritubular cells. Mol Hum Reprod, 24(8):401-410(2018) [pubmed]

curator keyword: Biological

submitter keyword: proteome, testis, marmoset monkey, DDA, MaxQuant, HTPC, MKTPC, peritubular testicular cells

Georg J. Arnold
contact affiliation	Laboratory for Functional Genome Analysis LAFUGA, Gene Center, LMU München, Fedor-Lynen-Strasse 25, 81377 Munich, Germany
contact email	arnold@genzentrum.lmu.de
lab head
Jan Bernd Stöckl
contact affiliation	Genzentrum der LMU München
contact email	stoeckl@genzentrum.lmu.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/06/PXD009394

PRIDE project URI

• PRIDE
  1. PXD009394
     1. Label: PRIDE project
     2. Name: Characterization of a nonhuman primate model for the study of testicular peritubular cells – comparison with human testicular cells