PXD009326-1

PXD009326 is an original dataset announced via ProteomeXchange.

Title	Mass Spectrometry Utilities: Fast post processing of mass spectrometry data.
Description	Development of Mass Spectrometry Utilities as a tool to complex MS data output as obtained from MaxQuant. As proof of concept the proteolytic degradation of glycerophosphoryl diester phosphodiesterase GlpQ by the protein quality control protease DegP is analyzed. Mass spectrometry was used to monitor proteolysis over time in the absence and presence of a peptidic allosteric activator of DegP. The software’s output clearly shows the increased proteolytic activity of DegP in the presence of the activating peptide, identifies statistically significant products of the proteolysis and offers insights into substrate specificity.
HostingRepository	PRIDE
AnnounceDate	2018-08-06
AnnouncementXML	Submission_2018-08-06_04:16:50.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Farnusch Kaschani
SpeciesList	scientific name: Escherichia coli; NCBI TaxID: 562;
ModificationList	monohydroxylated residue; acetylated residue
Instrument	LTQ Orbitrap Elite

Revision	Datetime	Status	ChangeLog Entry
0	2018-03-26 02:29:17	ID requested
⏵ 1	2018-08-06 04:16:51	announced
2	2024-10-22 04:44:07	announced	2024-10-22: Updated project metadata.

Bravo-Rodriguez K, Hagemeier B, Drescher L, Lorenz M, Rey J, Meltzer M, Kaschani F, Kaiser M, Ehrmann M, Utilities for Mass Spectrometry Analysis of Proteins (UMSAP): Fast post-processing of mass spectrometry data. Rapid Commun Mass Spectrom, 32(19):1659-1667(2018) [pubmed]

curator keyword: Technical

submitter keyword: MSU, data analysis, proteolysis, DegP, GlpQ

Farnusch Kaschani
contact affiliation	Analytics Core Facility Essen (ACE), Chemische Biologie, Universität Duisburg-Essen, ZMB, Germany
contact email	farnusch.kaschani@uni-due.de
lab head
Farnusch Kaschani
contact affiliation	University Duisburg-Essen
contact email	farnusch.kaschani@uni-due.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/08/PXD009326

PRIDE project URI

• PRIDE
  1. PXD009326
     1. Label: PRIDE project
     2. Name: Mass Spectrometry Utilities: Fast post processing of mass spectrometry data.