PXD009318-2

PXD009318 is an original dataset announced via ProteomeXchange.

Title	IgG-independent co-aggregation of FceRI and FcgRIIB results in LYN- and SHIP1-dependent tyrosine phosphorylation of FcgRIIB
Description	We used tyrosine phosphorylation profiling by anti-pTyr-antibody mediated enrichment and subsequent analysis by mass spectrometry in order to determine the changes in early signalling after mast cell activation. Mast cells were stimulated with varying concentrations of antigen for one minute and the differences between optimal (20 ng/ml) and supra-optimal (2000 ng/ml) antigen mast cell activation were analysed by nanoLC-MS/MS.
HostingRepository	PRIDE
AnnounceDate	2018-08-17
AnnouncementXML	Submission_2018-09-17_00:14:33.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Christian Preisinger
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	phosphorylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	LTQ Orbitrap Elite

Revision	Datetime	Status	ChangeLog Entry
0	2018-03-26 00:41:45	ID requested
1	2018-08-17 07:36:24	announced
⏵ 2	2018-09-17 00:14:35	announced	Updated publication reference for PubMed record(s): 30210494.
3	2024-10-22 04:44:15	announced	2024-10-22: Updated project metadata.

Gast M, Preisinger C, Nimmerjahn F, Huber M, RIIB in Murine Bone Marrow-Derived Mast Cells. Front Immunol, 9():1937(2018) [pubmed]

curator keyword: Biological

submitter keyword: Mouse, mast cell activation, tyrosine phosphorylation

Michael Huber
contact affiliation	Institute of Biochemistry and Molecular Immunology RWTH Aachen University Germany
contact email	mhuber@ukaachen.de
lab head
Christian Preisinger
contact affiliation	Proteomics Facility, IZKF Aachen, University Clinic RWTH Aachen
contact email	cpreisinger@ukaachen.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/08/PXD009318

PRIDE project URI

• PRIDE
  1. PXD009318
     1. Label: PRIDE project
     2. Name: IgG-independent co-aggregation of FceRI and FcgRIIB results in LYN- and SHIP1-dependent tyrosine phosphorylation of FcgRIIB