PXD009148 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | The endosomal proteome of LAMTOR2-deficient primary macrophages |
Description | A quantitative iTRAQ-based organelle proteomics analysis of endosomes derived from LAMTOR2-deficient macrophages has been performed. Primary macrophages were derived from bone marrow of conditional knockout mice carrying a specific deletion of LAMTOR2 in the monocyte/macrophage cell lineage. The combined proteomics and transcriptomics data indicated a function of LAMTOR2 in lipid metabolism. |
HostingRepository | PRIDE |
AnnounceDate | 2019-08-26 |
AnnouncementXML | Submission_2019-08-26_00:34:38.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Taras Stasyk |
SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; |
ModificationList | iTRAQ4plex-115 reporter fragment; monohydroxylated residue; iTRAQ4plex-116 reporter fragment; iodoacetamide derivatized residue |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2018-03-09 00:21:15 | ID requested | |
⏵ 1 | 2019-08-26 00:34:40 | announced | |
Publication List
Lamberti G, De Smet CH, Angelova M, Kremser L, Taub N, Herrmann C, Hess MW, Rainer J, Tancevski I, Schweigreiter R, Kofler R, Schmiedinger T, Vietor I, Trajanoski Z, Ejsing CS, Lindner HH, Huber LA, Stasyk T, LAMTOR/Ragulator regulates lipid metabolism in macrophages and foam cell differentiation. FEBS Lett, 594(1):31-42(2020) [pubmed] |
Keyword List
curator keyword: Biological |
submitter keyword: LAMTOR, Ragulator, Organelle proteomics, Macrophages, foam cells |
Contact List
Lukas A. Huber |
contact affiliation | Division of Cell Biology, Biocenter, Medical University of Innsbruck, Innsbruck, Austria |
contact email | lukas.a.huber@i-med.ac.at |
lab head | |
Taras Stasyk |
contact affiliation | Division of Cell Biology, Biocenter, Medical University of Innsbruck |
contact email | taras.stasyk@i-med.ac.at |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/08/PXD009148 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD009148
- Label: PRIDE project
- Name: The endosomal proteome of LAMTOR2-deficient primary macrophages