PXD009000 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Identification of MS-Cleavable and Non-Cleavable Chemically Crosslinked Peptides with MetaMorpheus |
Description | The present work describes a novel search program for the detection of both MS-cleavable and non-cleavable crosslinked peptides and it is the first software program reported with both capacities. The search strategy has been implemented in the computer program MetaMorpheus, which has a user-friendly graphical user interface (GUI). Novel crosslinker molecules can be easily added if desired. A fragment-ion index scheme makes the search computationally efficient. DSSO crosslinked BSA and E.coli ribosome data were used to validate the MS-cleavable crosslink search results. |
HostingRepository | PRIDE |
AnnounceDate | 2018-07-16 |
AnnouncementXML | Submission_2018-07-16_03:39:57.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Lei Lu |
SpeciesList | scientific name: Escherichia coli; NCBI TaxID: 562; |
ModificationList | monohydroxylated residue; iodoacetamide derivatized residue |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2018-02-21 02:33:00 | ID requested | |
⏵ 1 | 2018-07-16 03:39:58 | announced | |
Publication List
Dataset with its publication pending |
Keyword List
curator keyword: Technical |
submitter keyword: proteomics, MS-cleavable chemical crosslink, protein-protein interactions, ion index |
Contact List
Lloyd M Smith |
contact affiliation | Department of Chemistry, University of Wisconsin, Madison, Wisconsin 53706, United States |
contact email | smith@chem.wisc.edu |
lab head | |
Lei Lu |
contact affiliation | University of Wisconsin, Madison |
contact email | llu56@wisc.edu |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD009000
- Label: PRIDE project
- Name: Identification of MS-Cleavable and Non-Cleavable Chemically Crosslinked Peptides with MetaMorpheus