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PXD008959-1

PXD008959 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleSCI1 co-purifies with the STRIPAK protein PRO11
DescriptionThe STRIPAK complex is a conserved multi-protein complex, which is found in animals and in fungi but not in prokaryotes and plants. It is involved in growth and development, regulating signal transduction in cellular pathways, for example hippo and MAPK, and it has a role in human neuronal diseases, cell fusion, and cancer (1, 2). Small coiled-coil (CC) proteins were described in the STRIPAK complex of humans, in the Far complex of S. cerevisiae, in the SIP complex of S. pombe and in the STRIPAK complex of D. melanogaster (dSTRIPAK) (3-8). However, the function of small CC proteins in the STRIPAK complex is poorly investigated. We identified SCI1, a small CC protein belonging to the STRIPAK complex in the filamentous ascomycete S. macrospora. As all other STRIPAK components, SCI1 is required for development, hyphal fusion and vegetative growth.
HostingRepositoryPRIDE
AnnounceDate2018-08-21
AnnouncementXMLSubmission_2018-08-21_02:20:18.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterOliver Valerius
SpeciesList scientific name: Sordaria macrospora k-hell; NCBI TaxID: 771870;
ModificationListmonohydroxylated residue; iodoacetamide derivatized residue
InstrumentLTQ Orbitrap
Dataset History
RevisionDatetimeStatusChangeLog Entry
02018-02-14 07:05:24ID requested
12018-08-21 02:20:19announced
22018-11-13 23:46:14announcedUpdated publication reference for PubMed record(s): 30107058.
32024-10-22 04:43:11announced2024-10-22: Updated project metadata.
Publication List
Dataset with its publication pending
Keyword List
curator keyword: Biological
submitter keyword: STRIPAK, PRO11, SCI1, hyphal fusion, fruiting-body development, Sordaria macrospora
Contact List
Stefanie Pöggeler
contact affiliationGeorg-August University, Institute of Microbiology and Genetics, Grisebachstr. 8, D-37077 Göttingen, Germany
contact emailspoegge@gwdg.de
lab head
Oliver Valerius
contact affiliationGeorg-August-Universität Göttingen
contact emailovaleri@gwdg.de
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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