PXD008921-1
PXD008921 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | A new tool to reveal bacterial signaling mechanisms in antibiotic treatment and resistance |
| Description | Antimicrobial resistance is widespread across the globe. Here we presented a dynamic view of protein phosphoregulations during resistance development. Specific phosphorylation motifs and highly conserved phosphorylated residues on transcription factors were identified involving in regulating resistance for the first time implying the extent of phosphorylation regulation is far more important than we thought. Much effort need to be done in understanding the contribution of each signaling pathway to the development of resistance. Therefore, the dataset presented here could be a valuable resource for future works to decipher signaling mechanisms involved in AMR. |
| HostingRepository | jPOST |
| AnnounceDate | 2018-09-21 |
| AnnouncementXML | Submission_2018-09-20_19:47:19.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Non peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Miao-Hsia Lin |
| SpeciesList | scientific name: Escherichia coli; NCBI TaxID: 562; |
| ModificationList | S-carboxamidomethyl-L-cysteine; alpha-amino acetylated residue; L-methionine sulfoxide; O4'-phospho-L-tyrosine; O-phospho-L-serine; O-phospho-L-threonine; phosphorylated L-histidine; L-aspartic 4-phosphoric anhydride |
| Instrument | Q Exactive |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2018-02-09 12:37:57 | ID requested | |
| ⏵ 1 | 2018-09-20 19:47:20 | announced | |
| 2 | 2021-02-04 17:04:38 | announced | 2021-02-04: Updated FTP location. |
| 3 | 2022-09-18 02:49:34 | announced | 2022-09-18: Updated FTP location. |
Publication List
| Dataset with its publication pending |
Keyword List
| submitter keyword: antimicrobial resistance, phosphoproteomics, colistin, ciporlfoxacin |
Contact List
| Simone Lemeer | |
|---|---|
| lab head | |
| Miao-Hsia Lin | |
| contact affiliation | Institute of Chemistry, Academia Sinica |
| dataset submitter | |
Full Dataset Link List
| jPOST dataset URI |
| Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://jpost.pharm.kyoto-u.ac.jp/repository/JPST000388 |
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