PXD008835-2

PXD008835 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Data in support of Identification of brain antigens recognized by autoantibodies in experimental autoimmune encephalomyelitis-induced animals treated with Etomoxir or Interferon-beta
Description	Multiple Sclerosis is a neurogenerative disease, where inflammation plays an essential role and the loss of tolerance for self produces proteins is a key feature. To investigate the autoimmune response, we use serum from experimental autoimmune encephalomyelitis (EAE) induced rats and investigate autoantibody chance in connection with induced disease and treatment with Etomoxir or Interferon-beta. Several significant differences in suggested antigens were identified comparing healthy, diseased and treated groups, suggesting a role of these antigens in the progression of Multiple Sclerosis.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_03:59:18.787.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Allan Stensballe
SpeciesList	scientific name: Rattus norvegicus (Rat); NCBI TaxID: 10116;
ModificationList	iodoacetamide derivatized residue; deamidated residue; L-citrulline
Instrument	Q Exactive

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2018-02-01 09:42:40	ID requested
1	2018-05-14 02:32:00	announced
⏵ 2	2024-10-22 03:59:26	announced	2024-10-22: Updated project metadata.

Publication List

10.1038/s41598-018-25391-y;
M, ø, rkholt AS, Kastaniegaard K, Trabjerg MS, Gopalasingam G, Niganze W, Larsen A, Stensballe A, Nielsen S, Nieland JD, . Sci Rep, 8(1):7092(2018) [pubmed]

10.1038/s41598-018-25391-y;

M, ø, rkholt AS, Kastaniegaard K, Trabjerg MS, Gopalasingam G, Niganze W, Larsen A, Stensballe A, Nielsen S, Nieland JD, . Sci Rep, 8(1):7092(2018) [pubmed]

Keyword List

curator keyword: Biological, Biomedical
submitter keyword: Multiple Sclerosis, Autoantibodies, Experimental autoimmune encephalomyelitis, rat model, Inflammation, Autoantigens, Etomoxir

curator keyword: Biological, Biomedical

submitter keyword: Multiple Sclerosis, Autoantibodies, Experimental autoimmune encephalomyelitis, rat model, Inflammation, Autoantigens, Etomoxir

Contact List

Allan Stensballe
contact affiliation	Laboratory for Medical Mass Spectrometry Department of Health Science and Technology Aalborg University \| Denmark
contact email	as@hst.aau.dk
lab head
Allan Stensballe
contact affiliation	Aalborg University
contact email	as@hst.aau.dk
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/05/PXD008835
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/05/PXD008835

PRIDE project URI

Repository Record List

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