PXD008635 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Multiplexed proteome dynamics profiling of HSP90 inhibitor 17-AAG in T-cells |
Description | Investigation of proteostatic effects of HSP90 inhibition by 17-AAG and differentiation of maturation state dependent HSP90 requirements of proteins in resting T-cells. |
HostingRepository | PRIDE |
AnnounceDate | 2018-05-02 |
AnnouncementXML | Submission_2018-05-02_05:09:18.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Maria Faelth Savitski |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | 6x(13)C: 4x(15)N labeled L-arginine; methionine oxidation with neutral loss of 64 Da; 6x(13)C: 2x(15)N labeled L-lysine; 2x(13)C: 4x(2)H labeled dimethylated residue; acetylated residue; dimethylated residue; iodoacetamide derivatized residue |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2018-01-09 08:19:34 | ID requested | |
⏵ 1 | 2018-05-02 05:09:19 | announced | |
Publication List
Savitski MM, Zinn N, Faelth-Savitski M, Poeckel D, Gade S, Becher I, Muelbaier M, Wagner AJ, Strohmer K, Werner T, Melchert S, Petretich M, Rutkowska A, Vappiani J, Franken H, Steidel M, Sweetman GM, Gilan O, Lam EYN, Dawson MA, Prinjha RK, Grandi P, Bergamini G, Bantscheff M, Multiplexed Proteome Dynamics Profiling Reveals Mechanisms Controlling Protein Homeostasis. Cell, 173(1):260-274.e25(2018) [pubmed] |
Keyword List
curator keyword: Biomedical |
submitter keyword: 17-AAG, HSP90, mPDP, primary T-cells |
Contact List
Marcus Bantscheff |
contact affiliation | Cellzome |
contact email | marcus.x.bantscheff@gsk.com |
lab head | |
Maria Faelth Savitski |
contact affiliation | Cellzome |
contact email | maria.x.faelth-savitski@gsk.com |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/05/PXD008635 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD008635
- Label: PRIDE project
- Name: Multiplexed proteome dynamics profiling of HSP90 inhibitor 17-AAG in T-cells