PXD008575 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Mammalian proteome changes during oxidative stress and stress of the endoplasmic reticulum |
Description | Stress due to protein misfolding in the endoplasmic reticulum affects transcription and translation, RNA and protein degradation. By integrating several large-scale datasets, we quantified transcription, translation, RNA-protein binding events, and protein levels for several thousands of genes in HeLa cells. Here, we deposit the TMT-based, quantitative proteomics data consisting of two replicates with four measured time points collected for two stress treatments, i.e. tunicamycin and hydrogen peroxide. |
HostingRepository | PRIDE |
AnnounceDate | 2018-10-12 |
AnnouncementXML | Submission_2018-10-12_00:30:24.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Shuvadeep Maity |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | iodoacetamide derivatized residue |
Instrument | Orbitrap Fusion Lumos; Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2018-01-02 05:25:40 | ID requested | |
1 | 2018-10-11 09:57:37 | announced | |
⏵ 2 | 2018-10-12 00:30:26 | announced | Updated project metadata. |
Publication List
Rendleman J, Cheng Z, Maity S, Kastelic N, Munschauer M, Allgoewer K, Teo G, Zhang YBM, Lei A, Parker B, Landthaler M, Freeberg L, Kuersten S, Choi H, Vogel C, New insights into the cellular temporal response to proteostatic stress. Elife, 7():(2018) [pubmed] |
Keyword List
curator keyword: Biological, Biomedical |
submitter keyword: ER stress, Oxidative stress, Translation, Proteomics |
Contact List
Christine Vogel |
contact affiliation | New York University - Department of Biology, Center for Genomics & Systems Biology , New York, USA |
contact email | cvogel@nyu.edu |
lab head | |
Shuvadeep Maity |
contact affiliation | Associate research Scientist |
contact email | sm6622@nyu.edu |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/10/PXD008575 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD008575
- Label: PRIDE project
- Name: Mammalian proteome changes during oxidative stress and stress of the endoplasmic reticulum