PXD008510-1

PXD008510 is an original dataset announced via ProteomeXchange.

Title	Triatoma dimidiata salivary glands LC-MSMS
Description	The reduviid bug Triatoma dimidiata is an important Chagas disease vector widely distributed along Central America. This insect has great capability for domestic adaptation as the majority of specimens caught inside human dwellings or in peridomestic areas in Central America fed human blood. Within this context, exploring the salivary compounds that overcome host haemostatic and immune responses to assist blood-feeding is of great scientific interest. Our aim is to provide a deeper insight into T. dimidiata salivary gland molecules that may contribute to its haematophagic habit. We realized T. dimidiata salivary transcriptomic analysis and complemented it through proteomics, disclosing the set complexity of 119 secreted proteins. The large-scale approach used enriches the pharmacologically active molecules database and improves our knowledge about the complexity of salivary compounds from haematophagous vectors and their biological interactions.
HostingRepository	PRIDE
AnnounceDate	2018-01-04
AnnouncementXML	Submission_2018-01-04_03:07:06.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Carla Araújo
SpeciesList	scientific name: Triatoma dimidiata; NCBI TaxID: 72491;
ModificationList	No PTMs are included in the dataset
Instrument	LTQ Orbitrap Elite

Revision	Datetime	Status	ChangeLog Entry
0	2017-12-20 01:31:59	ID requested
⏵ 1	2018-01-04 03:07:07	announced

Santiago PB, de Ara, ú, jo CN, Charneau S, Bastos IMD, Assump, ç, ã, o TCF, Queiroz RML, Pra, ç, a YR, Cordeiro TM, Garcia CHS, da Silva IG, Raiol T, Motta FN, de Ara, ú, jo Oliveira JV, de Sousa MV, Ribeiro JMC, de Santana JM, Exploring the molecular complexity of Triatoma dimidiata sialome. J Proteomics, 174():47-60(2018) [pubmed]

curator keyword: Biological, Biomedical

submitter keyword: Triatoma dimidiata, Salivary glands, Saliva, LC-MSMS

Jaime Martins de Santana
contact affiliation	Host-Pathogen Interface Laboratory
contact email	jsantana@unb.br
lab head
Carla Araújo
contact affiliation	University of Brasilia
contact email	cnunes@unb.br
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/01/PXD008510

PRIDE project URI

• PRIDE
  1. PXD008510
     1. Label: PRIDE project
     2. Name: Triatoma dimidiata salivary glands LC-MSMS