PXD008281-1
PXD008281 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Identifying PTMs on PERIOD over a circadian day in Drosophila melanogaster |
| Description | Circadian clocks coordinate time-of-day specific metabolic and physiological processes to maximize performance and fitness. In addition to light, which is considered the strongest time cue to entrain animal circadian clocks, metabolic input has emerged as an important signal for clock modulation and entrainment, especially in peripheral clocks. Circadian clock proteins have been to be substrates of O-GlcNAcylation, a nutrient sensitive post-translational modification (PTM), and the interplay between clock protein O-GlcNAcylation and other PTMs, like phosphorylation, is expected to facilitate the regulation of circadian physiology by metabolic signals. Here, we used mass spectrometry proteomics to identify PTMs on PERIOD, the key biochemical timer of the Drosophila clock, over the circadian cycle. |
| HostingRepository | MassIVE |
| AnnounceDate | 2019-01-15 |
| AnnouncementXML | Submission_2019-01-15_21:13:39.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Non peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Joanna Chiu |
| SpeciesList | scientific name: Drosophila melanogaster; common name: fruit fly; NCBI TaxID: 7227; |
| ModificationList | Phospho |
| Instrument | LTQ Orbitrap Velos |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2017-11-23 14:25:42 | ID requested | |
| ⏵ 1 | 2019-01-15 21:13:39 | announced |
Publication List
| no publication |
Keyword List
| submitter keyword: Drosophila PERIOD, circadian rhythms |
Contact List
| Joanna Chiu | |
|---|---|
| contact affiliation | University of California, Davis |
| contact email | jcchiu@ucdavis.edu |
| lab head | |
| Joanna Chiu | |
| contact affiliation | University of California, Davis |
| contact email | yhli@ucdavis.edu |
| dataset submitter | |
Full Dataset Link List
| MassIVE dataset URI |
| Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/MSV000081736 |
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