PXD007841-1
PXD007841 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Comparative analysis of mRNA degradation and protein degradation in 68 pairs of adjacent prostate tissue samples indicates high stability of proteins |
Description | Here we investigated the degradation of mRNA and protein in 68 pairs of adjacent prostate tissue samples using RNA-seq and pressure cycling technology (PCT) coupled with SWATH mass spectrometry and developed a score, the Proteome Integrity Number (PIN), to quantify the extent of protein degradation in the samples. |
HostingRepository | PRIDE |
AnnounceDate | 2019-06-13 |
AnnouncementXML | Submission_2019-06-12_17:39:18.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Wenguang Shao |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | TripleTOF 5600 |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2017-09-26 01:52:09 | ID requested | |
⏵ 1 | 2019-06-12 17:39:19 | announced |
Publication List
Shao W, Guo T, Toussaint NC, Xue P, Wagner U, Li L, Charmpi K, Zhu Y, Wu J, Buljan M, Sun R, Rutishauser D, Hermanns T, Fankhauser CD, Poyet C, Ljubicic J, Rupp N, R, ü, schoff JH, Zhong Q, Beyer A, Ji J, Collins BC, Liu Y, R, ä, tsch G, Wild PJ, Aebersold R, Comparative analysis of mRNA and protein degradation in prostate tissues indicates high stability of proteins. Nat Commun, 10(1):2524(2019) [pubmed] |
Keyword List
curator keyword: Biomedical |
submitter keyword: DIA/SWATH |
clinical tissues |
protein stability |
Contact List
Ruedi Aebersold | |
---|---|
contact affiliation | Department of Biology, Institute of Molecular Systems Biology, ETH, Zurich, Switzerland |
contact email | aebersold@imsb.biol.ethz.ch |
lab head | |
Wenguang Shao | |
contact affiliation | ETH Zurich |
contact email | shaowenguang@gmail.com |
dataset submitter |
Full Dataset Link List
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/06/PXD007841 |
PRIDE project URI |
Repository Record List
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