PXD007548-3

PXD007548 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Quantitative Proteomic Analysis of Brucella abortus under Multiple Environmental Stresses
Description	We have used a multiple-environmental-stress strategy to reveal global metabolic adaptations of B. abortus to intravacuolar environmental conditions. These conditions included: (i) a Control condition (growth on TSB, condition #1); (ii) seven single-stress conditions: (condition #2-8) and (iii) a multi-stress condition (#9). The multi-stress was a combination of each single-stress that may better simulated the environments that Brucella may occur during the infection of a host. The proteomic analysis identified and quantified in total 2,272 proteins and 74% of the theoretical proteome, which is providing a wide coverage of B. abortus genome. The identification of proteins necessary for stress resistance is crucial to elucidate the infectious process in order to control brucellosis and may provide valuable clues towards discovery of novel therapeutic targets and effective vaccines.
HostingRepository	jPOST
AnnounceDate	2017-08-24
AnnouncementXML	Submission_2021-02-04_17:20:01.xml
DigitalObjectIdentifier
ReviewLevel	Non peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Xiaodong Zai
SpeciesList	scientific name: Brucella abortus; NCBI TaxID: 235;
ModificationList	S-carboxamidomethyl-L-cysteine; alpha-amino acetylated residue; L-methionine sulfoxide
Instrument	Q Exactive

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2017-08-24 03:58:35	ID requested
1	2017-08-24 03:58:39	announced
2	2018-09-19 00:25:33	announced	Updated CV, FTP location and Modification list.
⏵ 3	2021-02-04 17:20:01	announced	2021-02-04: Updated FTP location.
4	2022-09-18 03:46:11	announced	2022-09-18: Updated FTP location.

Publication List

Dataset with its publication pending

Dataset with its publication pending

Keyword List

submitter keyword: Brucella abortus, proteomic, label-free, environmental stress

submitter keyword: Brucella abortus, proteomic, label-free, environmental stress

Contact List

Xiaodong Zai
lab head
Xiaodong Zai
contact affiliation	Beijing Institute of Biotechnology
dataset submitter

Full Dataset Link List

jPOST dataset URI
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.biosciencedbc.jp/archive/jpostrepos/JPST000305

jPOST dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.biosciencedbc.jp/archive/jpostrepos/JPST000305