PXD007194 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | o Fra-2/AP-1 expression in collagen-producing macrophages mediates lung fibrosis development by inducing fibroblast activation |
| Description | Bronchioalveolar lavage-derived exosomes were isolated from Bleomycin-treated and Fra-2tg mouse lungs, two independent models of experimental lung fibrosis, and wild-type mouse lungs. Proteome of the exosome compartment was analysed by label-free LC MS/MS to look for differentially expressed proteins of the two lung fibrosis models compared to the wild-type controls. |
| HostingRepository | PRIDE |
| AnnounceDate | 2026-04-30 |
| AnnouncementXML | Submission_2026-04-30_04:44:56.681.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Pilar Ximenez-Embun |
| SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: NEWT:10090; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | LTQ Orbitrap Velos |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
| 0 | 2017-08-04 06:02:29 | ID requested | |
| ⏵ 1 | 2026-04-30 04:44:57 | announced | |
Publication List
Keyword List
| curator keyword: Biological |
| submitter keyword: Lung fibrosis |
| bronchioalveolar lavage |
| exosomes |
| LC-MS/MS |
Contact List
| Javier Munoz |
| contact affiliation | Spanish National Cancer Research Centre (CNIO), Spain |
| contact email | jmunozpe@cnio.es |
| lab head | |
| Pilar Ximenez-Embun |
| contact affiliation | Proteomics Group |
| contact email | mpximenez@cnio.es |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2026/04/PXD007194 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD007194
- Label: PRIDE project
- Name: o Fra-2/AP-1 expression in collagen-producing macrophages mediates lung fibrosis development by inducing fibroblast activation