PXD007103 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Endogenous Cell Type-Specific DISC1 Interactomes Reveal Protein Networks Associated to Neurodevelopmental Disorders |
Description | Disrupted in schizophrenia 1 (DISC1) has been implicated in contributing to a number of psychiatric diseases and neurodevelopmental phenotypes such as the proliferation and differentiation of neural progenitor cells. While there has been significant effort directed towards understanding the function of DISC1 through the determination of its protein-protein interactions within an in-vitro setting, endogenous interactions involving DISC1 within a cell-type specific setting relevant to neural development remain unclear. |
HostingRepository | PRIDE |
AnnounceDate | 2018-07-04 |
AnnouncementXML | Submission_2018-07-04_02:48:33.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Brent Wilkinson |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | LTQ FT |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2017-07-21 06:34:14 | ID requested | |
⏵ 1 | 2018-07-04 02:48:34 | announced | |
Publication List
Wilkinson B, Evgrafov OV, Zheng D, Hartel N, Knowles JA, Graham NA, Ichida JK, Coba MP, Endogenous Cell Type-Specific Disrupted in Schizophrenia 1 Interactomes Reveal Protein Networks Associated With Neurodevelopmental Disorders. Biol Psychiatry, 85(4):305-316(2019) [pubmed] |
Keyword List
curator keyword: Biomedical |
submitter keyword: neural, neural progenitor, disc1 |
Contact List
Marcelo Coba |
contact affiliation | University of Southern California |
contact email | coba@usc.edu |
lab head | |
Brent Wilkinson |
contact affiliation | University of Southern California |
contact email | brentwil@usc.edu |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/07/PXD007103 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD007103
- Label: PRIDE project
- Name: Endogenous Cell Type-Specific DISC1 Interactomes Reveal Protein Networks Associated to Neurodevelopmental Disorders