PXD006479 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Essential proteins' dynamics in Streptococcus sanguinis under antibiotic effect. |
Description | The current project investigates the proteomic profiles of essential genes, mass spectrometric analysis respectively, under impact of sub-inhibitory concentration of ampicillin (0.125 micro gm/ml), to elucidate the S. sanguinis stress response mechanisms on a temporal basis and define “pathogenesis signatures” as potential therapeutic targets. We further believe that the current findings will help characterize a bacterial model for studying the dynamics of essential genes under clinically relevant stress factors (antibiotic treatment) and assist in designing evidence-based guidelines for treatment in clinical settings. |
HostingRepository | PRIDE |
AnnounceDate | 2018-01-09 |
AnnouncementXML | Submission_2018-02-09_11:42:18.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Fadi El-Rami |
SpeciesList | scientific name: Streptococcus sanguinis SK36; NCBI TaxID: 388919; |
ModificationList | No PTMs are included in the dataset |
Instrument | Synapt MS |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2017-05-10 00:08:34 | ID requested | |
1 | 2018-01-09 08:28:16 | announced | |
⏵ 2 | 2018-02-09 11:42:19 | announced | Updated publication reference for PubMed record(s): 29393020. |
Publication List
El-Rami F, Kong X, Parikh H, Zhu B, Stone V, Kitten T, Xu P, Analysis of essential gene dynamics under antibiotic stress in Streptococcus sanguinis. Microbiology (Reading), 164(2):173-185(2018) [pubmed] |
Keyword List
curator keyword: Biomedical |
submitter keyword: Streptococcus sanguinis, essential genes, antibiotic, oral, stress |
Contact List
Ping Xu |
contact affiliation | Ping Xu, Professor VCU Philips Institute for Oral Health Research Microbiology and Immunology Virginia Commonwealth University Phone: 804-827-6264 Fax: 804-828-0150 |
contact email | pxu@vcu.edu |
lab head | |
Fadi El-Rami |
contact affiliation | Virginia Commonwealth University |
contact email | elramif@vcu.edu |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/01/PXD006479 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD006479
- Label: PRIDE project
- Name: Essential proteins' dynamics in Streptococcus sanguinis under antibiotic effect.