PXD006361-1

PXD006361 is an original dataset announced via ProteomeXchange.

Title	Proteomics reveals widespread modulation of protein SUMOylation by central DNA damage response kinases in response to replication stress
Description	The mechanisms that protect eukaryotic DNA duringdepend on several post-translational modifications (PTMs)-based signaling pathways. Phosphorylation is a well-known regulator of the replication stress response Here we investigate the global interplay between phosphorylation and SUMOylation in response to replication stress.
HostingRepository	PRIDE
AnnounceDate	2017-10-09
AnnouncementXML	Submission_2017-10-09_02:00:55.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Stephanie Munk
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	phosphorylated residue; sumoylated lysine; 6x(13)C labeled residue; iodoacetamide derivatized residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2017-04-24 03:54:48	ID requested
⏵ 1	2017-10-09 02:00:56	announced
2	2017-10-09 02:56:10	announced	Updated project metadata.

Dataset with its publication pending

curator keyword: Biological

submitter keyword: SUMO, phosphoproteomics, replication stress

Jesper V. Olsen
contact affiliation	1Proteomics program, Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark.
contact email	jesper.olsen@cpr.ku.dk
lab head
Stephanie Munk
contact affiliation	Copenhagen University
contact email	wtv380@cpr.ku.dk
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2017/10/PXD006361

PRIDE project URI

• PRIDE
  1. PXD006361
     1. Label: PRIDE project
     2. Name: Proteomics reveals widespread modulation of protein SUMOylation by central DNA damage response kinases in response to replication stress