PXD006305-1

PXD006305 is an original dataset announced via ProteomeXchange.

Title	Rat liver treated by PCN
Description	The combination analyses of transcriptomics, proteomics, phosphoproteomics, and metabolomics in rat liver after repeated oral doses of PXR agonist, PCN, for 7 days were conducted to understand the roles for PXR on non-genotoxic signaling and energy homeostasis. mRNA and proteins in homogenate supernatant, membrane, and cytosolic fractions prepared from the liver were analyzed.
HostingRepository	jPOST
AnnounceDate	2018-01-01
AnnouncementXML	Submission_2017-12-31_07:00:05.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Sumio Ohtsuki
SpeciesList	scientific name: Rattus rattus (Black rat); NCBI TaxID: 10117;
ModificationList	iodoacetamide derivatized residue; (2S,3R)-3-hydroxyaspartic acid; L-aspartic 4-phosphoric anhydride
Instrument	TripleTOF 5600

Revision	Datetime	Status	ChangeLog Entry
0	2017-04-14 21:25:55	ID requested
⏵ 1	2017-12-31 07:00:06	announced
2	2018-09-19 00:08:29	announced	Updated CV, FTP location and Modification list.
3	2021-02-04 16:58:57	announced	2021-02-04: Updated FTP location.
4	2022-09-18 02:44:46	announced	2022-09-18: Updated FTP location.

Nagahori H, Nakamura K, Sumida K, Ito S, Ohtsuki S, Combining Genomics To Identify the Pathways of Post-Transcriptional Nongenotoxic Signaling and Energy Homeostasis in Livers of Rats Treated with the Pregnane X Receptor Agonist, Pregnenolone Carbonitrile. J Proteome Res, 16(10):3634-3645(2017) [pubmed]

submitter keyword: rat, liver, PCN, SWATH, subcellular fractionation

Sumio Ohtsuki
lab head
Sumio Ohtsuki
contact affiliation	Kumamoto University
dataset submitter

jPOST dataset URI