PXD006236 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Accumulated ion monitoring for improved sensitivity |
| Description | This work aimed to improve sensitivity of targeted detection by orbitrap mass spectrometers. Co-isolation of contaminant ions was identified as the major factor limiting sensitivity, and LOD of both PRM and accumulated precursor ion scanning (AIM) was improved by increased chromatographic resolution. |
| HostingRepository | PRIDE |
| AnnounceDate | 2017-08-24 |
| AnnouncementXML | Submission_2017-08-24_02:19:04.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Alex Kentsis |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
| ModificationList | phosphorylated residue |
| Instrument | Orbitrap Fusion ETD |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2017-04-03 02:06:30 | ID requested | |
| ⏵ 1 | 2017-08-24 02:19:05 | announced | |
| 2 | 2024-10-22 04:02:20 | announced | 2024-10-22: Updated project metadata. |
Publication List
| Cifani P, Kentsis A, High Sensitivity Quantitative Proteomics Using Automated Multidimensional Nano-flow Chromatography and Accumulated Ion Monitoring on Quadrupole-Orbitrap-Linear Ion Trap Mass Spectrometer. Mol Cell Proteomics, 16(11):2006-2016(2017) [pubmed] |
Keyword List
| curator keyword: Technical |
| submitter keyword: targeted-MS, orbitrap, phosphorylation, quantitative-MS, PRM |
Contact List
| Alex Kentsis |
|---|
| contact affiliation | Molecular Pharmacology Program, Sloan-Kettering Institute, Memorial Sloan-Kettering Cancer Center, New York, NY, USA |
| contact email | kentsisresearchgroup@gmail.com |
| lab head | |
| Alex Kentsis |
|---|
| contact affiliation | Memorial Sloan Kettering Cancer Center |
| contact email | kentsisresearchgroup@gmail.com |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2017/08/PXD006236 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD006236
- Label: PRIDE project
- Name: Accumulated ion monitoring for improved sensitivity
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