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PXD006236 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleAccumulated ion monitoring for improved sensitivity
DescriptionThis work aimed to improve sensitivity of targeted detection by orbitrap mass spectrometers. Co-isolation of contaminant ions was identified as the major factor limiting sensitivity, and LOD of both PRM and accumulated precursor ion scanning (AIM) was improved by increased chromatographic resolution.
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterAlex Kentsis
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListphosphorylated residue
InstrumentOrbitrap Fusion ETD
Dataset History
RevisionDatetimeStatusChangeLog Entry
02017-04-03 02:06:30ID requested
12017-08-24 02:19:05announced
Publication List
Cifani P, Kentsis A, High Sensitivity Quantitative Proteomics Using Automated Multidimensional Nano-flow Chromatography and Accumulated Ion Monitoring on Quadrupole-Orbitrap-Linear Ion Trap Mass Spectrometer. Mol Cell Proteomics, 16(11):2006-2016(2017) [pubmed]
Keyword List
curator keyword: Technical
submitter keyword: targeted-MS, orbitrap, phosphorylation, quantitative-MS, PRM
Contact List
Alex Kentsis
contact affiliationMolecular Pharmacology Program, Sloan-Kettering Institute, Memorial Sloan-Kettering Cancer Center, New York, NY, USA
contact emailkentsisresearchgroup@gmail.com
lab head
Alex Kentsis
contact affiliationMemorial Sloan Kettering Cancer Center
contact emailkentsisresearchgroup@gmail.com
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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