PXD005949-1
PXD005949 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | Large-scale HDMSE mapping of the normal sputum proteome |
Description | Severe asthma is a collection of disease entities with varying pathophysiological characteristics that result in symptoms of cough, wheeze and breathlessness, with frequent exacerbations. To address the problem of phenotypic difference and heterogeneity, the Unbiased Biomarkers for the Prediction of Respiratory Disease Outcomes (U-BIOPRED) project was set up as a public-private partnership within the framework of the Innovative Medicines Initiative (IMI), engaging academia, the pharmaceutical industry and patient groups. The goal of this investigation was to identify proteomic fingerprints in induced sputum that characterize patients with severe asthma and to determine whether subgroups of severe asthmatics can be identified. Furthermore, we were interested in elucidating the biological pathways that showed differences between subgroups. This dataset is a description of the normal sputum proteome. |
HostingRepository | PRIDE |
AnnounceDate | 2018-05-14 |
AnnouncementXML | Submission_2018-05-14_03:05:59.xml |
DigitalObjectIdentifier | https://dx.doi.org/10.6019/PXD005949 |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Supported dataset by repository |
PrimarySubmitter | Paul Skipp |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | Carbamidomethyl |
Instrument | Synapt MS |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2017-02-22 03:18:31 | ID requested | |
⏵ 1 | 2018-05-14 03:06:00 | announced |
Publication List
Burg D, Schofield JPR, Brandsma J, Staykova D, Folisi C, Bansal A, Nicholas B, Xian Y, Rowe A, Corfield J, Wilson S, Ward J, Lutter R, Fleming L, Shaw DE, Bakke PS, Caruso M, Dahlen SE, Fowler SJ, Hashimoto S, Horv, á, th I, Howarth P, Krug N, Montuschi P, Sanak M, Sandstr, ö, m T, Singer F, Sun K, Pandis I, Auffray C, Sousa AR, Adcock IM, Chung KF, Sterk PJ, Djukanovi, ć R, Skipp PJ, The U-Biopred Study Group, Large-Scale Label-Free Quantitative Mapping of the Sputum Proteome. J Proteome Res, 17(6):2072-2091(2018) [pubmed] |
Keyword List
curator keyword: Biomedical |
submitter keyword: Sputum, Label free, Data independent, Human |
Contact List
Paul J S Skipp | |
---|---|
contact affiliation | Centre for Proteomic Research, Biological Sciences, University of Southampton |
contact email | pjss@soton.ac.uk |
lab head | |
Paul Skipp | |
contact affiliation | Centre for Proteomic Research, University of Southampton |
contact email | pjss@soton.ac.uk |
dataset submitter |
Full Dataset Link List
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/05/PXD005949 |
PRIDE project URI |
Repository Record List
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