PXD005360 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Proteomic Profiling of mouse High Grade Glioma |
| Description | High throughput proteomics profiling provide an unprecedented opportunity for dissecting molecular mechanisms in cancer biology. Here we present deep profiling of whole proteome and phosphoproteome in two high-grade glioma mouse models driven by mutated receptor tyrosine kinase (RTK) oncogenes. Using multiplex isobaric labeling (10-plex TMT) coupled with extensive liquid chromatography and mass spectrometry, we analyzed ~ 12K genes and > 30K phosphosites by extensive mass spectrometry. Systematical reprogramming of the proteome and phosphoproteome were observed in HGG tumors compare to normal cortex. |
| HostingRepository | PRIDE |
| AnnounceDate | 2019-06-24 |
| AnnouncementXML | Submission_2019-06-24_08:44:48.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | xusheng wang |
| SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; |
| ModificationList | phosphorylated residue; monohydroxylated residue |
| Instrument | Q Exactive |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2016-11-16 02:11:21 | ID requested | |
| ⏵ 1 | 2019-06-24 08:44:49 | announced | |
Publication List
| Dataset with its publication pending |
Keyword List
| curator keyword: Biomedical |
| submitter keyword: Genomics, proteomics, genome, proteome, transcriptome, phosphoproteome, mass spectrometry, RNAseq, brain tumor, high-grade glioma (HGG), cancer driver, PDGFRA, and NTRK |
Contact List
| Junmin Peng |
|---|
| contact affiliation | St. Jude Children's Research Hospital |
| contact email | junmin.peng@stjude.org |
| lab head | |
| xusheng wang |
|---|
| contact affiliation | Proteomics |
| contact email | xushengwang78@gmail.com |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2019/06/PXD005360 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD005360
- Label: PRIDE project
- Name: Proteomic Profiling of mouse High Grade Glioma
to receive all new ProteomeXchange dataset release announcements!
