PXD005160 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Seminal fluid proteome of the polyandrous Red junglefowl |
Description | We characterized the SF proteome of the polyandrous Red junglefowl, Gallus gallus, the wild species that gave rise to the domestic chicken. We identify 1,141 SFPs, including proteins involved in immunity and antimicrobial defences, sperm maturation, and fertilisation, revealing a functionally complex SF proteome. This includes a predominant contribution of blood plasma proteins that is conserved with human SF. By comparing the proteome of young and old males with fast or slow sperm velocity in a balanced design, we identify proteins associated with ageing and sperm velocity, and show that old males that retain high sperm velocity have distinct proteome characteristics. SFP comparisons with domestic chickens revealed both qualitative and quantitative differences likely associated with domestication and artificial selection. Collectively, these results shed light onto the functional complexity of avian SF, and provide a platform for molecular studies of fertility, reproductive ageing, and domestication. |
HostingRepository | PRIDE |
AnnounceDate | 2017-10-24 |
AnnouncementXML | Submission_2017-10-24_04:00:14.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Emma Whittington |
SpeciesList | scientific name: Gallus gallus (Chicken); NCBI TaxID: 9031; |
ModificationList | No PTMs are included in the dataset |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2016-10-17 01:10:22 | ID requested | |
1 | 2017-01-03 03:34:46 | announced | |
⏵ 2 | 2017-10-24 04:00:16 | announced | Updated project metadata. |
3 | 2017-10-24 06:05:16 | announced | Updated project metadata. |
Publication List
Borziak K, Á, lvarez-Fern, á, ndez A, L Karr T, Pizzari T, Dorus S, The Seminal fluid proteome of the polyandrous Red junglefowl offers insights into the molecular basis of fertility, reproductive ageing and domestication. Sci Rep, 6():35864(2016) [pubmed] |
Keyword List
curator keyword: Biological |
submitter keyword: red junglefowl, seminal fluid, proteomics, fertility, reproductive ageing, domestication |
Contact List
Dr Steve Dorus |
contact affiliation | Syracuse University |
contact email | sdorus@syr.edu |
lab head | |
Emma Whittington |
contact affiliation | Syracuse Univeristy |
contact email | ewhittin@syr.edu |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2016/12/PXD005160 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD005160
- Label: PRIDE project
- Name: Seminal fluid proteome of the polyandrous Red junglefowl