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PXD005104-2

PXD005104 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleThe CVSC mechanically reinforces HSV-1
DescriptionUsing atomic force microscopy imaging and nanoindentation measurements, the effect of the minor capsid proteins pUL17 and pUL25 on the structural stability of the icosahedral Herpes Simplex Virus type 1 capsids was investigated. pUL17 and pUL25 that form the capsid vertex-specific component particularly contributed to the capsid resilience along the 5-fold and 2-fold, but not the 3-fold icosahedral axes. We tested whether deletion of UL17 and UL25 changed the levels of the proteins that assemble in the nucleocapsid by quantitative mass spectrometry.
HostingRepositoryPRIDE
AnnounceDate2024-10-22
AnnouncementXMLSubmission_2024-10-22_04:28:23.451.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterEleonora Corradini
SpeciesList scientific name: Herpes simplex virus (type 1 / strain F); NCBI TaxID: 10304;
ModificationListiodoacetamide derivatized residue
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02016-10-05 23:58:10ID requested
12017-04-20 00:16:41announced
22024-10-22 04:28:23announced2024-10-22: Updated project metadata.
Publication List
Dataset with its publication pending
Keyword List
curator keyword: Biological
submitter keyword: HSV-1, LC-MS/MS
Contact List
Albert J.R. Heck
contact affiliationBiomolecular mass spectrometry and proteomics, Utrecht University, Utrecht, The Netherlands
contact emaila.j.r.heck@uu.nl
lab head
Eleonora Corradini
contact affiliationBiomolecular and mass spectrometry group
contact emaile.corradini1@uu.nl
dataset submitter
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Dataset FTP location
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PRIDE project URI
Repository Record List
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