PXD004935 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | The EML4-ALK Interactome in Lung Cancer |
Description | We experimentally generated an ALK interactome combining quantitative tyrosine phosphoproteomics and protein complex annotation using affinity purification coupled with mass spectrometry and further investigated downstream ALK signaling using quantitative tyrosine phosphoproteomics. |
HostingRepository | PRIDE |
AnnounceDate | 2018-10-26 |
AnnouncementXML | Submission_2018-10-26_13:55:08.xml |
DigitalObjectIdentifier | https://dx.doi.org/10.6019/PXD004935 |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Supported dataset by repository |
PrimarySubmitter | John Koomen |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | LTQ Orbitrap |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2016-09-12 03:04:26 | ID requested | |
⏵ 1 | 2018-10-26 13:55:09 | announced | |
Publication List
Zhang G, Scarborough H, Kim J, Rozhok AI, Chen YA, Zhang X, Song L, Bai Y, Fang B, Liu RZ, Koomen J, Tan AC, Degregori J, Haura EB, Coupling an EML4-ALK-centric interactome with RNA interference identifies sensitizers to ALK inhibitors. Sci Signal, 9(450):rs12(2016) [pubmed] |
Keyword List
curator keyword: Biological, Biomedical |
submitter keyword: Human, Lung Cancer, EML4-ALK, Interactome |
Contact List
Eric B. Haura, MD |
contact affiliation | Thoracic Oncology Chemical Biology and Molecular Medicine Program Moffitt Cancer Center |
contact email | eric.haura@moffitt.org |
lab head | |
John Koomen |
contact affiliation | Moffitt Cancer Center |
contact email | john.koomen@moffitt.org |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/10/PXD004935 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD004935
- Label: PRIDE project
- Name: The EML4-ALK Interactome in Lung Cancer