PXD004808 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Penguin plasma LC-MSMS |
Description | While safety of fasting therapy is debated in humans, extended fasting occurs routinely and safely in wild animals. To do so, food deprived animals like breeding penguins anticipate the critical limit of fasting by resuming feeding. To date, however, no molecular indices of the physiological state that links spontaneous refeeding behaviour with fasting limits had been identified. Blood proteomics and physiological data reveal here that fasting-induced body protein depletion is not unsafe “per se”. Indeed, incubating penguins only abandon their chick/egg to refeed when this state is associated with metabolic defects in glucose homeostasis/fatty acid utilization, insulin production and action, and possible renal dysfunctions. Our data illustrate how the field investigation of “exotic” models can be a unique source of information, with possible biomedical interest. |
HostingRepository | PRIDE |
AnnounceDate | 2017-01-02 |
AnnouncementXML | Submission_2017-01-02_12:12:23.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Fabrice BERTILE |
SpeciesList | scientific name: Pygoscelis adeliae; NCBI TaxID: 9238; |
ModificationList | monohydroxylated residue; acetylated residue; iodoacetamide derivatized residue |
Instrument | Bruker Daltonics HCT Series |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2016-08-15 06:20:06 | ID requested | |
⏵ 1 | 2017-01-02 12:12:24 | announced | |
2 | 2017-10-24 04:16:08 | announced | Updated project metadata. |
Publication List
Bertile F, Fouillen L, Wasselin T, Maes P, Le Maho Y, Van Dorsselaer A, Raclot T, The Safety Limits Of An Extended Fast: Lessons from a Non-Model Organism. Sci Rep, 6():39008(2016) [pubmed] |
Keyword List
curator keyword: Biological |
submitter keyword: Adélie Penguin, plasma, 2D gels, LC-MSMS |
Contact List
Sarah Cianférani |
contact affiliation | Laboratoire de Spectrométrie de Masse BioOrganique, Analytical Science department, IPHC, CNRS, Strasbourg University, UMR7178, Strasbourg, France |
contact email | sarah.cianferani@unistra.fr |
lab head | |
Fabrice BERTILE |
contact affiliation | CNRS |
contact email | fbertile@unistra.fr |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD004808
- Label: PRIDE project
- Name: Penguin plasma LC-MSMS