PXD004510 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Mapping and Quantification of Brain Protein O-GlcNAcylation in Alzheimer’s Disease |
| Description | Comprehensive, quantitative proteomics analysis of protein O-GlcNAcylation in post-mortem human brains with and without Alzheimer’s using isobaric tandem mass tags labeling, chemoenzymatic photocleavage enrichment and liquid chromatography coupled to mass spectrometry. |
| HostingRepository | PRIDE |
| AnnounceDate | 2017-09-04 |
| AnnouncementXML | Submission_2017-09-04_05:35:52.xml |
| DigitalObjectIdentifier | https://dx.doi.org/10.6019/PXD004510 |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Supported dataset by repository |
| PrimarySubmitter | Matthew Monroe |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
| ModificationList | TMT6plex; Oxidation; AMTzHexNAc2; Carbamidomethyl |
| Instrument | LTQ Orbitrap Velos |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2016-07-04 07:55:41 | ID requested | |
| ⏵ 1 | 2017-09-04 05:35:53 | announced | |
| 2 | 2024-10-22 04:39:52 | announced | 2024-10-22: Updated project metadata. |
Publication List
| Wang S, Yang F, Petyuk VA, Shukla AK, Monroe ME, Gritsenko MA, Rodland KD, Smith RD, Qian WJ, Gong CX, Liu T, Quantitative proteomics identifies altered O-GlcNAcylation of structural, synaptic and memory-associated proteins in Alzheimer's disease. J Pathol, 243(1):78-88(2017) [pubmed] |
Keyword List
| submitter keyword: O-GlcNAc, Alzheimer's disease, brain |
Contact List
| Tao Liu |
|---|
| contact affiliation | Pacific Northwest National Laboratory |
| contact email | tao.liu@pnnl.gov |
| lab head | |
| Matthew Monroe |
|---|
| contact affiliation | Biological Separations & Mass Spectrometry |
| contact email | matthew.monroe@pnnl.gov |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2017/09/PXD004510 |
| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD004510
- Label: PRIDE project
- Name: Mapping and Quantification of Brain Protein O-GlcNAcylation in Alzheimer’s Disease
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