PXD004475 is an
original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Comparative proteomics analysis of Desulfovibrio vulgaris Hildenborough in response to the antimicrobial agent, free nitrous acid |
| Description | Sulfate reducing bacteria (SRB), which can produce hydrogen sulfide in sewers, can lead to severe odor problems and asset deterioration due to the sulfide induced concrete corrion. Recently, free nitrou acid (FNA) has been discovered as a promising antimicrobial agent to inhibit SRB activities thereby limiting sulfide production in sewers. However, knowledge of bacteria response dynamics to the increasing levels of FNA is largely unkown.In this study, we detected the whole cell protein production and protein expression dynamics of D. vulgaris by SWATH-MS in the presence of four FNA concentrations (0, 1.0, 4.0 and 8.0 μg N/L) with three treatment time peirods after FNA addition (2, 8 and 12 h). From this a more comprehensive understanding of the FNA effects on D. vulgaris was obtained and the key determinants for withstanding FNA over incubation periods were verified in this sewer corrosion relevant strain. |
| HostingRepository | PRIDE |
| AnnounceDate | 2025-11-28 |
| AnnouncementXML | Submission_2025-11-28_02:22:04.923.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Shuhong Gao |
| SpeciesList | scientific name: Escherichia coli; NCBI TaxID: NEWT:562; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | TripleTOF 5600 |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|
| 0 | 2016-06-30 06:55:23 | ID requested | |
| ⏵ 1 | 2025-11-28 02:22:05 | announced | |
Publication List
| 10.1016/j.scitotenv.2019.03.442; |
| Gao SH, Ho JY, Fan L, Nouwens A, Hoelzle RD, Schulz B, Guo J, Zhou J, Yuan Z, Bond PL, A comparative proteomic analysis of Desulfovibrio vulgaris Hildenborough in response to the antimicrobial agent free nitrous acid. Sci Total Environ, 672():625-633(2019) [pubmed] |
Keyword List
| curator keyword: Biomedical |
| submitter keyword: proteomics, free nitrous acid,Desulfovibrio vulgaris |
Contact List
| Shuhong Gao |
|---|
| contact affiliation | Advanced Water Managment Center, The University of Queensland |
| contact email | s.gao@awmc.uq.edu.au |
| lab head | |
| Shuhong Gao |
|---|
| contact affiliation | The University of Queensland |
| contact email | gaoshuhong1127@163.com |
| dataset submitter | |
Full Dataset Link List
Dataset FTP location
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| PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD004475
- Label: PRIDE project
- Name: Comparative proteomics analysis of Desulfovibrio vulgaris Hildenborough in response to the antimicrobial agent, free nitrous acid
