PXD004435-2

PXD004435 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Transcription factor-SNP interactome for colorectal cancer risk loci
Description	A core task to understand the consequences of non-coding single nucleotide polymorphisms (SNP) is to identify their genotype specific binding of transcription factor (TF). Here, we generate a large-scale TF-SNP interaction map for a selection of 116 colorectal cancer (CRC) risk loci and validated TF binding to 10 putatively functional SNPs. Our data further revealed TF binding complexity adjacent to the 116 risk loci, adding an additional layer of understanding to regulatory networks associated with CRC relevant loci.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_04:30:32.309.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Ning Qing Liu
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	2x(13)C,4x(2)H labeled dimethylated L-lysine; acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2016-06-24 03:59:28	ID requested
1	2017-02-23 03:44:53	announced
⏵ 2	2024-10-22 04:30:32	announced	2024-10-22: Updated project metadata.

Publication List

Dataset with its publication pending

Dataset with its publication pending

Keyword List

curator keyword: Biological, Biomedical
submitter keyword: Human, transcription factor, cancer related SNP, colorectal cancer

curator keyword: Biological, Biomedical

submitter keyword: Human, transcription factor, cancer related SNP, colorectal cancer

Contact List

Ning Qing Liu
contact affiliation	Department of Molecular Biology, Radboud Institute for Molecular Life Sciences
contact email	n.liu@ncmls.ru.nl
lab head
Ning Qing Liu
contact affiliation	Radboud Institute of Molecular Life Sciences
contact email	n.liu@ncmls.ru.nl
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2017/02/PXD004435
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2017/02/PXD004435

PRIDE project URI

Repository Record List

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