PXD004434 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Human milk oligosaccharides and infant fecal oligosaccharides |
Description | In this study, we quantitated the disappearance of intact HMOs and characterized the glycan digestion products in the gut that are produced by the action of microbial enzymes on HMOs and glycoconjugates from breast milk. Oligosaccharides from fecal samples of exclusively breast-fed infants were extracted and profiled using nanoLC-MS. Intact HMOs were found in the fecal samples, additionally, other oligosaccharides were found corresponding to degraded HMOs and non-HMO based compounds. The latter compounds were fragments of N-glycans released through the cleavage of the linkage to the asparagine residue and through cleavage of the chitobiose core of the N-glycan. |
HostingRepository | PRIDE |
AnnounceDate | 2016-07-26 |
AnnouncementXML | Submission_2016-07-26_03:12:52.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Jasmine Davis |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | 6520 Quadrupole Time-of-Flight LC/MS; 6220 Time-of-Flight LC/MS |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2016-06-24 03:56:21 | ID requested | |
⏵ 1 | 2016-07-26 03:12:54 | announced | |
Publication List
Davis JC, Totten SM, Huang JO, Nagshbandi S, Kirmiz N, Garrido DA, Lewis ZT, Wu LD, Smilowitz JT, German JB, Mills DA, Lebrilla CB, Identification of Oligosaccharides in Feces of Breast-fed Infants and Their Correlation with the Gut Microbial Community. Mol Cell Proteomics, 15(9):2987-3002(2016) [pubmed] |
Keyword List
submitter keyword: oligosaccharide, milk, feces, liquid chromatography, mass spectrometry |
Contact List
Carlito B. Lebrilla |
contact affiliation | Chemistry Department, University of California, Davis, USA |
contact email | cblebrilla@ucdavis.edu |
lab head | |
Jasmine Davis |
contact affiliation | University of California, Davis |
contact email | jccdavis@ucdavis.edu |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2016/07/PXD004434 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD004434
- Label: PRIDE project
- Name: Human milk oligosaccharides and infant fecal oligosaccharides