PXD004332-1

PXD004332 is an original dataset announced via ProteomeXchange.

Title	Proteome map of adult human pituitary glands
Description	The regulation of pituitary function via the hypothalamus and via intra-pituitary connections represents a complex system. Though hormones secreted from the anterior and posterior pituitary have been well studied, overall information of proteins expressed in the anterior and posterior pituitary gland is very limited. Protein expression profiling of normal pituitary tissue may lead to discovery of novel proteins playing an important role in the physiology of pituitary glands and can lead to better understanding of pituitary diseases. We aimed to carry out systematic proteomic profiling of adenohypophysis from human pituitary glands using high-resolution Fourier transform mass spectrometer. A total of 2,051 proteins were identified in this study of which, 653 proteins were identified for the first time from human pituitary gland. The comprehensive list of proteins identified in this study, many for the first time, will facilitate the better understanding the role of this important gland in health and disease.
HostingRepository	PRIDE
AnnounceDate	2017-01-03
AnnouncementXML	Submission_2017-01-03_02:54:44.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Keshava Prasad T. S.
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	LTQ Orbitrap Velos

Revision	Datetime	Status	ChangeLog Entry
0	2016-06-15 03:12:31	ID requested
⏵ 1	2017-01-03 02:54:47	announced
2	2019-12-16 06:42:28	announced	2019-12-16: Updated project metadata.
3	2024-10-22 04:36:20	announced	2024-10-22: Updated project metadata.

Yelamanchi SD, Kumar M, Madugundu AK, Gopalakrishnan L, Dey G, Chavan S, Sathe G, Mathur PP, Gowda H, Mahadevan A, Shankar SK, Prasad TS, Characterization of human pineal gland proteome. Mol Biosyst, 12(12):3622-3632(2016) [pubmed]

curator keyword: Biological

submitter keyword: Human, Pituitary, Gland, Tissue, LC-MS/MS

T. S. Keshava Prasad
contact affiliation	Institute of Bioinformatics, International Technology Park, Bangalore 560 066, India
contact email	keshav@ibioinformatics.org
lab head
Keshava Prasad T. S.
contact affiliation	Institute of Bioinformatics, Bangalore, Karnataka, India.
contact email	keshav@ibioinformatics.org
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2016/12/PXD004332

PRIDE project URI

• PRIDE
  1. PXD004332
     1. Label: PRIDE project
     2. Name: Proteome map of adult human pituitary glands