PXD004055 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Large-scale phosphorylation site interaction proteomics |
Description | Receptor tyrosine kinases (RTKs) are membrane proteins that regulate complex, multilayered signaling networks centered on tyrosine phosphorylation of proteins with broad implications in human health and disease. Here we developed a large-scale mass spectrometry-based proteomics platform for investigation of in-vivo RTK signaling networks and the dynamic protein interactions they induce. |
HostingRepository | PRIDE |
AnnounceDate | 2019-10-04 |
AnnouncementXML | Submission_2019-10-07_01:40:46.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Christian Kelstrup |
SpeciesList | scientific name: Rattus norvegicus (Rat); NCBI TaxID: 10116; |
ModificationList | phosphorylated residue; iodoacetamide derivatized residue |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2016-04-26 05:47:06 | ID requested | |
1 | 2019-10-04 03:56:27 | announced | |
⏵ 2 | 2019-10-07 01:40:48 | announced | 2019-10-07: Updated publication reference for PubMed record(s): 31585087.
2019-10-07: Updated publication reference for DOI(s): https://doi.org/10.1016/j.cell.2019.09.008. |
3 | 2023-05-15 01:51:36 | announced | 2023-05-15: Updated project metadata. |
4 | 2023-11-14 08:49:07 | announced | 2023-11-14: Updated project metadata. |
Publication List
https://doi.org/10.1016/j.cell.2019.09.008; |
Lundby A, Franciosa G, Emdal KB, Refsgaard JC, Gnosa SP, Bekker-Jensen DB, Secher A, Maurya SR, Paul I, Mendez BL, Kelstrup CD, Francavilla C, Kveiborg M, Montoya G, Jensen LJ, Olsen JV, Oncogenic Mutations Rewire Signaling Pathways by Switching Protein Recruitment to Phosphotyrosine Sites. Cell, 179(2):543-560.e26(2019) [pubmed] |
Keyword List
curator keyword: Biological |
submitter keyword: phosphorylation |
interaction proteomics |
Contact List
Jesper V. Olsen |
contact affiliation | The Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Denmark |
contact email | jesper.olsen@cpr.ku.dk |
lab head | |
Christian Kelstrup |
contact affiliation | University of Copenhagen |
contact email | chdake@cpr.ku.dk |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD004055
- Label: PRIDE project
- Name: Large-scale phosphorylation site interaction proteomics