PXD004054 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | SILAC analysis of Δhmt1 yeast |
Description | In this study, the proteome-level effects of the deletion of the gene encoding Hmt1p, the predominant yeast arginine methyltransferase, were measured using SILAC (stable isotope labeling by amino acids in cell culture), to clarify if the abundance levels of any proteins were disrupted by systemic loss of arginine methylation. Analysis revealed that numerous proteins were found to be differentially abundant between wild-type yeast and Δhmt1, and functional analysis revealed perturbation of phosphate signalling and repression of the PHO pathway. |
HostingRepository | PRIDE |
AnnounceDate | 2018-11-21 |
AnnouncementXML | Submission_2018-11-21_06:21:28.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Daniel Yagoub |
SpeciesList | scientific name: Saccharomyces cerevisiae (Baker's yeast); NCBI TaxID: 4932; |
ModificationList | monohydroxylated residue; iodoacetamide derivatized residue |
Instrument | LTQ Orbitrap Velos |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2016-04-26 04:07:53 | ID requested | |
⏵ 1 | 2018-11-21 06:21:29 | announced | |
Publication List
Chia SZ, Lai YW, Yagoub D, Lev S, Hamey JJ, Pang CNI, Desmarini D, Chen Z, Djordjevic JT, Erce MA, Hart-Smith G, Wilkins MR, Leads to the Dysregulation of Phosphate-associated Genes and Processes. Mol Cell Proteomics, 17(12):2462-2479(2018) [pubmed] |
Keyword List
curator keyword: Biological |
submitter keyword: SILAC, yeast, HMT1, arginine methylation, methylation, phosphate |
Contact List
Marc Roland Wilkins |
contact affiliation | Systems Biology Initiative, University of New South Wales, Australia |
contact email | m.wilkins@unsw.edu.au |
lab head | |
Daniel Yagoub |
contact affiliation | University of New South Wales |
contact email | daniel.yagoub@gmail.com |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2018/11/PXD004054 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD004054
- Label: PRIDE project
- Name: SILAC analysis of Δhmt1 yeast